Molecule Details
| InChIKey | GWCYPEHWIZXYFZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | Masupirdine |
| Canonical SMILES | COc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccccc1Br |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.11 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB06140 |
|---|---|
| Drug Name | SUVN-502 |
| CAS Number | 701205-60-9 |
| Groups | investigational |
| ATC Codes | nan |
| Description | SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer’s and Schizophrenia, an unmet medical need. |
Categories: Antidepressive Agents Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Neurotransmitter Agents Serotonin Agents Serotonin Receptor Antagonists
Cross-references: CHEMBL4117187 ChemSpider: 8249313
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P50406 | HTR6 | 5-hydroxytryptamine receptor 6 | antagonist | targets |