2-Methyl-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

InChIKey	`GVKXHJBRWOYLAK-UHFFFAOYSA-N`
Compound Name	2-Methyl-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Canonical SMILES	`Cc1cc(-c2cnn3cc(N4CCC(N5CCN(C)CC5)CC4)cnc23)c2ccccc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.76
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q04771	ACVR1	Homo sapiens	Human	PF01064 PF07714 PF08515	7.8	IC50	ChEMBL;BindingDB
P37023	ACVRL1	Homo sapiens	Human	PF07714 PF08515	6.5	IC50	BindingDB
P36896	ACVR1B	Homo sapiens	Human	PF01064 PF00069 PF08515	6.0	IC50	ChEMBL;BindingDB