Molecule Details
| InChIKey | GVJYOLRRZZUUOE-AATRIKPKSA-N |
|---|---|
| Compound Name | 6-[(E)-but-2-enyl]-4-[4-(2-hydroxypropan-2-yl)-2-methoxyphenyl]-1H-pyrrolo[2,3-c]pyridin-7-one |
| Canonical SMILES | C/C=C/Cn1cc(-c2ccc(C(C)(C)O)cc2OC)c2cc[nH]c2c1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.53 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9H8M2 | BRD9 | Homo sapiens | Human | PF00439 PF12024 | 7.5 | IC50 | ChEMBL |
| Q9NPI1 | BRD7 | Homo sapiens | Human | PF00439 PF12024 | 6.5 | Kd | ChEMBL |
| Q92830 | KAT2A | Homo sapiens | Human | PF00583 PF00439 PF06466 | 6.4 | Kd | ChEMBL |
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 6.2 | Kd | ChEMBL |
| Q58F21 | BRDT | Homo sapiens | Human | PF17035 PF17105 PF00439 | 6.1 | Kd | ChEMBL |