Molecule Details
InChIKeyGUMBHNMWKMFKRT-UHFFFAOYSA-N
Compound Name4-(4-Fluorophenyl)thieno[2,3-c]pyridine-2-carboxamide
Canonical SMILESNC(=O)c1cc2c(-c3ccc(F)cc3)cncc2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Cross-Family
Avg pChEMBL6.4
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.6 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.4 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q96KB5 PBK Homo sapiens Human PF00069 6.2 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.1 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.1 Ki ChEMBL
Q96RG2 PASK Homo sapiens Human PF13426 PF00069 6.1 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.1 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL