Molecule Details
InChIKeyGTQPEQGDLVSFJO-CXAGYDPISA-N
Canonical SMILESCc1cnc(-c2cc(O[C@@H]3CCOC3)cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)c2)s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.45
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21465
Drug NameEliapixant
CAS Number1948229-21-7
Groups investigational
ATC Codes nan
DescriptionEliapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Eliapixant is a purinoreceptor (P2X) antagonist. Eliapixant is under investigation in clinical trial NCT04614246 (Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice D...

Cross-references: BindingDB: 319844 CHEMBL5095224
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P56373 P2RX3 Homo sapiens Human PF00864 8.1 IC50 ChEMBL;BindingDB
Q9UBL9 P2RX2 Homo sapiens Human PF00864 6.8 IC50 ChEMBL;BindingDB