Molecule Details
| InChIKey | GTIRCXWYMTWWRW-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[3,5-Bis(trifluoromethyl)phenyl]-1-hydroxy-2-naphthamide |
| Canonical SMILES | O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc2ccccc2c1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.36 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P56373 | P2RX3 | Homo sapiens | Human | PF00864 | 6.7 | IC50 | ChEMBL;BindingDB |
| P51575 | P2RX1 | Homo sapiens | Human | PF00864 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q99571 | P2RX4 | Homo sapiens | Human | PF00864 | 6.1 | IC50 | ChEMBL;BindingDB |
| Q99572 | P2RX7 | Homo sapiens | Human | PF20478 PF00864 | 6.1 | IC50 | ChEMBL;BindingDB |