GRQLDCHTDNYVQI-UHFFFAOYSA-N — MultiTargetDB

Molecule Details

InChIKey	`GRQLDCHTDNYVQI-UHFFFAOYSA-N`
Canonical SMILES	`N=C(N)c1ccc2cccc(Nc3ncccn3)c2c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.75
Source	ChEMBL;BindingDB

2D Structure

2D structure

Activity Profile

DrugBank Annotations

DrugBank ID	DB04059
Drug Name	8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide
CAS Number	nan
Groups	experimental
ATC Codes	nan
Description	nan

Cross-references: BindingDB: 50147086 ChEBI: 46311 CHEMBL103043 ChemSpider: 395358 PDB: UI2 PubChem:448610 PubChem:46506499 ZINC: ZINC000005933825

Target Activities (2)

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00749	PLAU	Homo sapiens	Human	PF00051 PF00089	7.5	Ki	ChEMBL;BindingDB
P06870	KLK1	Homo sapiens	Human	PF00089	6.0	Ki	ChEMBL;BindingDB

DrugBank Target Actions (1)

Target	Gene	Target Name	Action	Type
P00749	PLAU	Urokinase-type plasminogen activator	binder	targets