4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide

InChIKey	`GQLPTZZPKXZFQR-UHFFFAOYSA-N`
Compound Name	4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide
Canonical SMILES	`Cc1cc(COc2ccc(S(=O)(=O)NCc3n[nH]c(=O)[nH]3)cc2)c2ccccc2n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.22
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P78536	ADAM17	Homo sapiens	Human	PF16698 PF00200 PF13574	6.4	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	6.2	pIC50	TTD_MultiTarget
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	6.2	Ki	ChEMBL;BindingDB
P09237	MMP7	Homo sapiens	Human	PF00413 PF01471	6.0	Ki	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	6.2	pIC50	TTD_MultiTarget