(16E)-14-methyl-11-(2-piperidin-1-ylethoxy)-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene

InChIKey	`GOWRQMXPMZRPRM-ONEGZZNKSA-N`
Compound Name	(16E)-14-methyl-11-(2-piperidin-1-ylethoxy)-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene
Canonical SMILES	`CN1C/C=C/CCOc2cccc(c2)-c2ccnc(n2)Nc2ccc(OCCN3CCCCC3)c(c2)C1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	6.92
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	7.3	IC50	ChEMBL;BindingDB
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	7.2	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	7.2	pIC50	TTD_MultiTarget
Q02161	RHD	Homo sapiens	Human	PF00909	6.9	pIC50	TTD_MultiTarget
P24941	CDK2	Homo sapiens	Human	PF00069	6.6	pIC50	TTD_MultiTarget
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	6.6	IC50	ChEMBL
P78396	CCNA1	Homo sapiens	Human	PF02984 PF00134 PF16500	6.6	IC50	ChEMBL