Molecule Details
InChIKeyGOTMKOSCLKVOGG-OAHLLOKOSA-N
Compound NameR-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol
Canonical SMILESCN1CCc2cc(Cl)c(O)cc2[C@@H](c2ccccc2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.34
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P21918 DRD5 Homo sapiens Human PF00001 9.3 Ki ChEMBL;BindingDB
P21728 DRD1 Homo sapiens Human PF00001 9.1 Ki ChEMBL;BindingDB
P28223 HTR2A Homo sapiens Human PF00001 7.9 Ki BindingDB
P28335 HTR2C Homo sapiens Human PF00001 7.4 Ki BindingDB
P41595 HTR2B Homo sapiens Human PF00001 7.2 Ki BindingDB
Q99720 SIGMAR1 Homo sapiens Human PF04622 6.4 IC50 ChEMBL;BindingDB
P35462 DRD3 Homo sapiens Human PF00001 6.3 Ki BindingDB
P14416 DRD2 Homo sapiens Human PF00001 6.3 Ki ChEMBL;BindingDB
P08908 HTR1A Homo sapiens Human PF00001 6.2 Ki BindingDB