Molecule Details
| InChIKey | GOAZOFMNXDONAU-UHFFFAOYSA-N |
|---|---|
| Compound Name | {2-[(4-Chlorophenyl)methoxy]phenyl}{5-[2-(Methylamino)-1,3-Thiazol-4-Yl]-2,3-Dihydro-1h-Indol-1-Yl}methanone |
| Canonical SMILES | CNc1nc(-c2ccc3c(c2)CCN3C(=O)c2ccccc2OCc2ccc(Cl)cc2)cs1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.78 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y3S1 | WNK2 | Homo sapiens | Human | PF24889 PF12202 PF00069 | 7.3 | IC50 | BindingDB |
| Q9H4A3 | WNK1 | Homo sapiens | Human | PF24889 PF12202 PF00069 | 6.8 | IC50 | ChEMBL;BindingDB |
| Q96J92 | WNK4 | Homo sapiens | Human | PF24889 PF12202 PF00069 | 6.7 | IC50 | BindingDB |
| P55011 | SLC12A2 | Homo sapiens | Human | PF00324 PF08403 PF03522 | 6.6 | IC50 | ChEMBL |
| Q9BYP7 | WNK3 | Homo sapiens | Human | PF24889 PF12202 PF00069 | 6.4 | IC50 | BindingDB |