Molecule Details
| InChIKey | GNOZTUOADYKOFQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7-(4-Fluorophenyl)-5-(4-methylphenyl)pyrido[2,3-d]pyrimidin-4-ylamine |
| Canonical SMILES | Cc1ccc(-c2cc(-c3ccc(F)cc3)nc3ncnc(N)c23)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.62 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y5X4 | NR2E3 | Homo sapiens | Human | PF00104 PF00105 | 6.8 | IC50 | ChEMBL;BindingDB |
| P37231 | PPARG | Homo sapiens | Human | PF00104 PF12577 PF00105 | 6.7 | IC50 | ChEMBL |
| Q9Y618 | NCOR2 | Homo sapiens | Human | PF15784 PF00249 | 6.7 | IC50 | ChEMBL;BindingDB |
| Q14289 | PTK2B | Homo sapiens | Human | PF21477 PF00373 PF18038 PF03623 PF07714 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q05397 | PTK2 | Homo sapiens | Human | PF21477 PF00373 PF18038 PF03623 PF07714 | 6.5 | IC50 | BindingDB |