Molecule Details
| InChIKey | GNMUEVRJHCWKTO-FQEVSTJZSA-N |
|---|---|
| Compound Name | (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetamide |
| Canonical SMILES | Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1ccc(O)cc1)c1nnc(C)n1-2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.78 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB15189 |
|---|---|
| Drug Name | Birabresib |
| CAS Number | 202590-98-5 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)). |
Categories: Amides Amines Anilides Aniline Compounds Heterocyclic Compounds, Fused-Ring
Cross-references: BindingDB: 50092312 ChEBI: 191051 CHEMBL3581647 ChemSpider: 8112374 PDB: 6JE Wikipedia: Birabresib ZINC: ZINC000003960759