Molecule Details
| InChIKey | GNLUTCWCOCLPIJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(5-Methylcarbamoyl-1h-benzoimidazol-2-yl)-6-(2-methoxy-4 hydroxyphenyl)-1h-indazole |
| Canonical SMILES | CNC(=O)c1ccc2[nH]c(-c3n[nH]c4cc(-c5ccc(O)cc5OC)ccc34)nc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.45 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11802 | CDK4 | Homo sapiens | Human | PF00069 | 7.7 | Ki | ChEMBL |
| P24385 | CCND1 | Homo sapiens | Human | PF02984 PF00134 | 7.7 | Ki | ChEMBL |
| P30281 | CCND3 | Homo sapiens | Human | PF02984 PF00134 | 7.7 | Ki | ChEMBL |
| P20248 | CCNA2 | Homo sapiens | Human | PF02984 PF00134 PF16500 | 7.1 | Ki | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 7.1 | Ki | ChEMBL |