InChIKey	GMRQFYUYWCNGIN-NKMMMXOESA-N
Compound Name	Calcitriol
Canonical SMILES	C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]23)C[C@@H](O)C[C@@H]1O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.13
Source	BindingDB;ChEMBL

DrugBank ID	DB00136
Drug Name	Calcitriol
CAS Number	32222-06-3
Groups	approved investigational nutraceutical
ATC Codes	D05AX03 A11CC04
Description	Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin D<sub>3</sub>. It is produced in the body after series of conversion steps of 7-dehydrocholeste...

---

Categories: Alimentary Tract and Metabolism Antipsoriatics Antipsoriatics for Topical Use Bone Density Conservation Agents Calcium-Regulating Hormones and Agents Cholestanes Cholestenes Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Diet, Food, and Nutrition Food Fused-Ring Compounds Growth Substances Lipids Membrane Lipids Membrane Transport Modulators Micronutrients Misc. Skin and Mucous Membrane Agents Physiological Phenomena Secosteroids Steroids Sterols Vitamin D and Analogues Vitamins Vitamins (Fat Soluble)

---

Cross-references: BindingDB: 50200182 ChEBI: 17823 CHEMBL846 ChemSpider: 4444108 Drugs Product Database (DPD): 4893 Guide to Pharmacology: 2779 IUPHAR: 2779 C01673 D00129 PDB: VDX PharmGKB: PA448717 PubChem:5280453 PubChem:46508162 RxCUI: 1894 Therapeutic Targets Database: DAP000289 Wikipedia: Calcitriol ZINC: ZINC000100015048