Molecule Details
InChIKeyGLMWKEAUVZDGKE-UHFFFAOYSA-N
Compound Name(4-Chloropyrido[4,3-b][1,4]benzothiazin-10-yl)-(4-methoxyphenyl)methanone
Canonical SMILESCOc1ccc(C(=O)N2c3ccccc3Sc3c(Cl)cncc32)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Cross-Family
Avg pChEMBL6.4
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 7.2 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.8 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.8 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.7 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.7 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.4 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.3 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.2 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.1 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.0 Ki ChEMBL