Molecule Details
InChIKeyGLLPUTYLZIKEGF-HAVVHWLPSA-N
Compound NameRidogrel
Canonical SMILESO=C(O)CCCCO/N=C(/c1cccnc1)c1cccc(C(F)(F)F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.25
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01207
Drug NameRidogrel
CAS Number110140-89-1
Groups experimental
ATC Codes nan
DescriptionRidogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. However, there currently are no clinical indications for preferential use of ridogrel over aspirin.

Categories: Acids, Acyclic Antiplatelet agents Enzyme Inhibitors Fatty Acids Fatty Acids, Volatile Gastrointestinal Agents Hematologic Agents Lipids Thromboxane-A Synthase, antagonists & inhibitors Valerates
Cross-references: BindingDB: 50003795 ChEBI: 135542 CHEMBL280728 ChemSpider: 4515025 PharmGKB: PA164746413 PubChem:5362391 PubChem:46506774 Therapeutic Targets Database: DAP000469 ZINC: ZINC000001536934
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P24557 TBXAS1 Homo sapiens Human PF00067 8.2 IC50 ChEMBL;BindingDB
P21731 TBXA2R Homo sapiens Human PF00001 6.3 Kd ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P21731 TBXA2R Thromboxane A2 receptor antagonist targets
P24557 TBXAS1 Thromboxane-A synthase inhibitor targets