N-(3-tert-butyl-1-phenylpyrazol-5-yl)-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]benzamide

InChIKey	`GLDPXWNDIUPOHH-UHFFFAOYSA-N`
Compound Name	N-(3-tert-butyl-1-phenylpyrazol-5-yl)-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]benzamide
Canonical SMILES	`CC(C)(C)c1cc(NC(=O)c2cccc(Oc3cccc4[nH]c(=O)[nH]c34)c2)n(-c2ccccc2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	6.53
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04049	RAF1	Homo sapiens	Human	PF00130 PF07714 PF02196	6.9	IC50	ChEMBL;BindingDB
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.7	IC50	ChEMBL;BindingDB
P15056	BRAF	Homo sapiens	Human	PF00130 PF07714 PF02196	6.5	IC50	ChEMBL
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	6.0	IC50	ChEMBL;BindingDB
P11362	FGFR1	Homo sapiens	Human	PF07679 PF00047 PF07714	Clinical	TTD_MultiTarget	TTD_MultiTarget
Q5VT25	CDC42BPA	Homo sapiens	Human	PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433	Clinical	TTD_MultiTarget	TTD_MultiTarget