Molecule Details
| InChIKey | GLBYQIQGWFGGQH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(3-Bromo-4-hydroxy-phenyl)-N-(2-{2-[3-(3-bromo-4-hydroxy-phenyl)-2-hydroxyimino-propionylamino]-ethyldisulfanyl}-ethyl)-2-[(E)-hydroxyimino]-propionamide |
| Canonical SMILES | O=NC(Cc1ccc(O)c(Br)c1)C(=O)NCCSSCCNC(=O)C(Cc1ccc(O)c(Br)c1)N=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.39 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 7.9 | IC50 | BindingDB |
| P26358 | DNMT1 | Homo sapiens | Human | PF01426 PF06464 PF00145 PF12047 PF02008 | 7.7 | IC50 | BindingDB |
| Q92769 | HDAC2 | Homo sapiens | Human | PF00850 | 7.5 | IC50 | BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 7.3 | IC50 | BindingDB |
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 6.5 | IC50 | BindingDB |