Molecule Details
InChIKeyGLBJJMFZWDBELO-UHFFFAOYSA-N
Canonical SMILESCOc1ccc(-c2nc3cc(C4=NNC(=O)CC4C)ccc3[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.39
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11450
Drug NamePimobendan
CAS Number74150-27-9
Groups experimental vet_approved
ATC Codes nan
Descriptionnan

Categories: Cardiotonic Agents Cardiovascular Agents Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 Substrates Enzyme Inhibitors Phosphodiesterase Inhibitors Protective Agents Vasodilating Agents
Cross-references: BindingDB: 50282617 ChEBI: 32003 CHEMBL24646 ChemSpider: 4657 Drugs Product Database (DPD): 13253 D01133 RxCUI: 1110783 Wikipedia: Pimobendan
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13370 PDE3B Homo sapiens Human PF00233 6.4 IC50 ChEMBL
Q14432 PDE3A Homo sapiens Human PF00233 6.4 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P05177 CYP1A2 Cytochrome P450 1A2 substrate enzymes