Molecule Details
InChIKeyGKPHAIOJCHBZCT-HXUWFJFHSA-N
Canonical SMILESCc1ccc(C(=O)N2CCOC[C@H]2Cc2cccc(-n3nccn3)c2)c(-n2nccn2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.63
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21506
Drug NameNivasorexant
CAS Number1435480-40-2
Groups experimental
ATC Codes nan
DescriptionNivasorexant is a small molecule drug. The usage of the INN stem '-orexant' in the name indicates that Nivasorexant is a orexin receptor antagonist. Nivasorexant has a monoisotopic molecular weight of 429.19 Da.

Cross-references: BindingDB: 183990 CHEMBL3892369
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O43613 HCRTR1 Homo sapiens Human PF00001 8.7 IC50 ChEMBL;BindingDB
O43614 HCRTR2 Homo sapiens Human PF00001 PF03827 6.6 IC50 ChEMBL;BindingDB