Molecule Details
InChIKeyGKDBTHSYQZTDAJ-UHFFFAOYSA-N
Compound Name2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-ethoxy)-4-methyl-quinolin-6-yl]-acetamide
Canonical SMILESCc1cc(OCCN(C)C)nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Homologous
Avg pChEMBL8.79
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P28222 HTR1B Homo sapiens Human PF00001 9.7 IC50 ChEMBL;BindingDB
P08913 ADRA2A Homo sapiens Human PF00001 9.6 IC50 ChEMBL
P18089 ADRA2B Homo sapiens Human PF00001 9.6 IC50 ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 9.6 IC50 ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 9.2 IC50 ChEMBL;BindingDB
P25021 HRH2 Homo sapiens Human PF00001 9.1 IC50 ChEMBL;BindingDB
P35462 DRD3 Homo sapiens Human PF00001 8.9 IC50 ChEMBL;BindingDB
P11229 CHRM1 Homo sapiens Human PF00001 8.8 IC50 ChEMBL;BindingDB
P35367 HRH1 Homo sapiens Human PF00001 8.5 IC50 ChEMBL;BindingDB
P08172 CHRM2 Homo sapiens Human PF00001 8.3 IC50 ChEMBL;BindingDB
P21728 DRD1 Homo sapiens Human PF00001 8.1 IC50 ChEMBL;BindingDB
Q969V1 MCHR2 Homo sapiens Human PF00001 8.1 IC50 ChEMBL;BindingDB
Q99705 MCHR1 Homo sapiens Human PF00001 6.9 IC50 ChEMBL;BindingDB