Molecule Details
InChIKeyGJFCSAPFHAXMSF-UXBLZVDNSA-N
Compound NameJnk-IN-8
Canonical SMILESCc1cc(NC(=O)c2cccc(NC(=O)/C=C/CN(C)C)c2)ccc1Nc1nccc(-c2cccnc2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.35
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P53779 MAPK10 Homo sapiens Human PF00069 9.0 IC50 ChEMBL;BindingDB
P45983 MAPK8 Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
P45984 MAPK9 Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB