Molecule Details
| InChIKey | GHYCWVRIEDGGFQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-3-hydroxy-3-(tetrahydro-2h-pyran-4-yl)-2h-indol-2-one |
| Canonical SMILES | Cc1noc(C)c1-c1ccc2c(c1)C(O)(C1CCOCC1)C(=O)N2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.44 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15059 | BRD3 | Homo sapiens | Human | PF17035 PF00439 | 6.8 | IC50 | ChEMBL;BindingDB |
| P25440 | BRD2 | Homo sapiens | Human | PF17035 PF00439 | 6.4 | IC50 | ChEMBL;BindingDB |
| Q58F21 | BRDT | Homo sapiens | Human | PF17035 PF17105 PF00439 | 6.3 | IC50 | ChEMBL;BindingDB |
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 6.2 | IC50 | ChEMBL;BindingDB |