Molecule Details
InChIKeyGFVIEZBZIUKYOG-SVFBPWRDSA-N
Compound NameN-Acetyl-3-Methyl-L-Valyl-(4r)-4-Hydroxy-N-[4-(4-Methyl-1,3-Thiazol-5-Yl)benzyl]-L-Prolinamide
Canonical SMILESCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.53
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15369 ELOC Homo sapiens Human PF03931 6.8 Kd ChEMBL;BindingDB
Q15370 ELOB Homo sapiens Human PF00240 6.8 Kd ChEMBL
P40337 VHL Homo sapiens Human PF01847 PF17211 6.7 Kd ChEMBL;BindingDB
Q13617 CUL2 Homo sapiens Human PF00888 PF26557 PF10557 6.2 IC50 BindingDB
Q16665 HIF1A Homo sapiens Human PF23171 PF11413 PF08778 PF00989 PF08447 6.1 IC50 ChEMBL;BindingDB