5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)pyrimidin-2-amine

InChIKey	`GFMLSFXYFKGRNS-UHFFFAOYSA-N`
Compound Name	5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)pyrimidin-2-amine
Canonical SMILES	`CN1CCN(CCc2ccc(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)cc2)CC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.15
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P06493	CDK1	Homo sapiens	Human	PF00069	8.2	pIC50	TTD_MultiTarget
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	8.2	IC50	ChEMBL;BindingDB