Molecule Details
InChIKeyGFIQKTNEPGLOBO-PGUFJCEWSA-N
Compound NameN-(7-{4-[2-(4-Chloro-phenyl)-5,5-dimethyl-cyclohex-1-enylmethyl]-piperazin-1-yl}quinazolin-4-yl)-4-((R)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-trifluoromethanesulfonyl-benzenesulfonamide
Canonical SMILESCN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncnc3cc(N4CCN(CC5=C(c6ccc(Cl)cc6)CCC(C)(C)C5)CC4)ccc23)cc1S(=O)(=O)C(F)(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.79
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q07817 BCL2L1 Homo sapiens Human PF00452 PF02180 8.5 IC50 ChEMBL;BindingDB
P10415 BCL2 Homo sapiens Human PF00452 PF02180 8.3 IC50 ChEMBL;BindingDB
Q92843 BCL2L2 Homo sapiens Human PF00452 PF02180 6.6 IC50 ChEMBL;BindingDB