Molecule Details
InChIKeyGEQMDKKVXALFFX-UHFFFAOYSA-N
Compound Name5-chloro-4-(1,3-dimethylpyrazol-4-yl)-N-(1-methylsulfonylpiperidin-4-yl)pyrimidin-2-amine
Canonical SMILESCc1nn(C)cc1-c1nc(NC2CCN(S(C)(=O)=O)CC2)ncc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL8.05
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 8.7 Ki ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 8.7 Ki ChEMBL
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 7.9 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 7.9 Ki ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 7.9 Ki ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 7.9 Ki ChEMBL
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 7.8 Ki ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 7.8 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.8 Ki ChEMBL