Molecule Details
| InChIKey | GEPUTKWSUKGITG-UHFFFAOYSA-N |
|---|---|
| Compound Name | n-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-2-yl)pyrazin-2-yl]cyclopropane-carboxamide |
| Canonical SMILES | O=C(Nc1cnc(-c2ccncc2F)c(-c2ncco2)n1)C1CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.67 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P29275 | ADORA2B | Homo sapiens | Human | PF00001 | 8.2 | Ki | ChEMBL;BindingDB |
| P29274 | ADORA2A | Homo sapiens | Human | PF00001 | 6.4 | Ki | ChEMBL;BindingDB |
| P0DMS8 | ADORA3 | Homo sapiens | Human | PF00001 | 6.0 | Ki | ChEMBL;BindingDB |
| P33261 | CYP2C19 | Homo sapiens | Human | PF00067 | 6.0 | IC50 | ChEMBL;BindingDB |