Molecule Details
InChIKeyGDTQLZHHDRRBEB-UHFFFAOYSA-N
Canonical SMILESCCCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CC4)ccc3C)c2c1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.55
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12696
Drug NameBMS-582949
CAS Number623152-17-0
Groups investigational
ATC Codes nan
DescriptionBMS-582949 has been investigated for the treatment of Psoriasis.

Categories: Mitogen-Activated Protein Kinase 14, antagonists & inhibitors
Cross-references: BindingDB: 50327009 CHEMBL1230065 ChemSpider: 8584505 PDB: 38P PubChem:10409068 PubChem:347828897 ZINC: ZINC000036475284
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 7.9 IC50 ChEMBL;BindingDB
Q15759 MAPK11 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB