(2S,3R)-N-hydroxy-3-(2-methylpropyl)-N'-[(2S)-1-oxo-3-phenyl-1-(1,3-thiazol-2-yl)propan-2-yl]-2-prop-2-enylbutanediamide

InChIKey	`GCGWPKSFLVGEQR-OTWHNJEPSA-N`
Compound Name	(2S,3R)-N-hydroxy-3-(2-methylpropyl)-N'-[(2S)-1-oxo-3-phenyl-1-(1,3-thiazol-2-yl)propan-2-yl]-2-prop-2-enylbutanediamide
Canonical SMILES	`C=CC[C@H](C(=O)NO)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)c1nccs1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	6.5
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P09237	MMP7	Homo sapiens	Human	PF00413 PF01471	6.7	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	6.4	pIC50	TTD_MultiTarget
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	6.4	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	6.4	pIC50	TTD_MultiTarget