Molecule Details
| InChIKey | GBOGMAARMMDZGR-TYHYBEHESA-N |
|---|---|
| Compound Name | Cytochalasin B |
| Canonical SMILES | C=C1[C@@H](C)[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@]23OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C/C=C/[C@H]3[C@@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.69 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16766 |
|---|---|
| Drug Name | Cytochalasin B |
| CAS Number | 14930-96-2 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Categories: Biological Factors Cytochalasins Heterocyclic Compounds, Fused-Ring Indoles Mycotoxins Toxins, Biological
Cross-references: BindingDB: 50478403 ChEBI: 23527 CHEMBL411729 ChemSpider: 4470791 PDB: 5RH Wikipedia: Cytochalasin_B ZINC: ZINC000003932776
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11166 | SLC2A1 | Homo sapiens | Human | PF00083 | 7.0 | IC50 | ChEMBL |
| P11169 | SLC2A3 | Homo sapiens | Human | PF00083 | 6.9 | IC50 | ChEMBL |
| P14672 | SLC2A4 | Homo sapiens | Human | PF00083 | 6.5 | IC50 | ChEMBL |
| P20701 | ITGAL | Homo sapiens | Human | PF01839 PF08441 PF20805 PF00357 PF00092 | 6.3 | IC50 | BindingDB |