Molecule Details
| InChIKey | GBDNHNNAGDSWAW-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(2-methoxyphenyl)-8,9-dihydro-7H-[1,4]dioxepino[2,3-g][3,1]benzoxazin-4-one |
| Canonical SMILES | COc1ccccc1-c1nc2cc3c(cc2c(=O)o1)OCCCO3 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.37 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49862 | KLK7 | Homo sapiens | Human | PF00089 | 7.1 | Ki | ChEMBL;BindingDB |
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 6.2 | Ki | BindingDB |
| P08311 | CTSG | Homo sapiens | Human | PF00089 | 6.2 | Ki | ChEMBL;BindingDB |
| Q9Y337 | KLK5 | Homo sapiens | Human | PF00089 | 6.0 | Ki | ChEMBL;BindingDB |