Molecule Details
| InChIKey | GASCXMZEQJQACK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-amino-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrazol-3-yl thiophene-2-carboxylate |
| Canonical SMILES | COc1ccc(S(=O)(=O)n2nc(OC(=O)c3cccs3)cc2N)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.39 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07858 | CTSB | Homo sapiens | Human | PF00112 PF08127 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q9Y337 | KLK5 | Homo sapiens | Human | PF00089 | 6.1 | IC50 | BindingDB |
| P06935 | West Nile virus | Pathogen | PF20907 PF01003 PF07652 PF21659 PF02832 PF00869 PF01004 PF00948 PF01005 PF01002 PF01350 PF01349 PF00972 PF20483 PF01570 PF01728 PF00949 | 7.0 | IC50 | ChEMBL;BindingDB |