Molecule Details
InChIKeyGARXJOUQUSNOGK-UHFFFAOYSA-N
Compound NameN-(4-(Methoxymethyl)-1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide
Canonical SMILESCCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2ccccc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.3
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB09179
Drug NameR-30490
CAS Number60618-49-7
Groups experimental
ATC Codes nan
DescriptionR-30490 is an opioid related to carfentanil used as an animal tranquilizer. It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives. R-30490 was found to be the most selective agonist for the mu opioid receptor out of all t...

Categories: Piperidines
Cross-references: CHEMBL609147 ChemSpider: 111042 PubChem:124716 PubChem:310265087 Wikipedia: R-30490
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P35372 OPRM1 Homo sapiens Human PF00001 10.1 Ki ChEMBL
P41143 OPRD1 Homo sapiens Human PF00001 7.6 Ki ChEMBL
P41145 OPRK1 Homo sapiens Human PF00001 7.2 Ki ChEMBL