Molecule Details
| InChIKey | GAOYFSUEXBKHRD-UHFFFAOYSA-N |
|---|---|
| Compound Name | methyl N'-[2-[[methylsulfanyl-[(6-sulfamoyl-1,3-benzothiazol-2-yl)amino]methylidene]amino]ethyl]-N-(6-sulfamoyl-1,3-benzothiazol-2-yl)carbamimidothioate |
| Canonical SMILES | CS/C(=N\c1nc2ccc(S(N)(=O)=O)cc2s1)NCCN/C(=N/c1nc2ccc(S(N)(=O)=O)cc2s1)SC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.24 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 8.6 | Ki | ChEMBL;BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 8.5 | Ki | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 8.3 | Ki | ChEMBL;BindingDB |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 7.6 | Ki | ChEMBL;BindingDB |