{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-carbamic acid 2-(4-cyano-phenyl)-ethyl ester

InChIKey	`GALCSZPFCCZIBC-UHFFFAOYSA-N`
Compound Name	{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-carbamic acid 2-(4-cyano-phenyl)-ethyl ester
Canonical SMILES	`N#Cc1ccc(CCOC(=O)NC2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	6.33
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60840	CACNA1F	Homo sapiens	Human	PF08763 PF16885 PF16905 PF00520	6.5	IC50	ChEMBL
Q01668	CACNA1D	Homo sapiens	Human	PF08763 PF16885 PF16905 PF00520	6.5	IC50	ChEMBL
Q13698	CACNA1S	Homo sapiens	Human	PF08763 PF16905 PF00520	6.5	IC50	ChEMBL
Q13936	CACNA1C	Homo sapiens	Human	PF08763 PF16885 PF16905 PF00520	6.5	IC50	ChEMBL;BindingDB
P25021	HRH2	Homo sapiens	Human	PF00001	6.4	IC50	ChEMBL;BindingDB
P21728	DRD1	Homo sapiens	Human	PF00001	6.4	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.4	pIC50	TTD_MultiTarget
P25100	ADRA1D	Homo sapiens	Human	PF00001	6.4	IC50	ChEMBL
P35348	ADRA1A	Homo sapiens	Human	PF00001	6.4	pIC50	TTD_MultiTarget
P35368	ADRA1B	Homo sapiens	Human	PF00001	6.4	IC50	ChEMBL
P50406	HTR6	Homo sapiens	Human	PF00001	6.4	IC50	ChEMBL;BindingDB
P35367	HRH1	Homo sapiens	Human	PF00001	6.3	IC50	ChEMBL;BindingDB
P21918	DRD5	Homo sapiens	Human	PF00001	6.3	IC50	ChEMBL;BindingDB
P35462	DRD3	Homo sapiens	Human	PF00001	6.3	IC50	ChEMBL;BindingDB
P14416	DRD2	Homo sapiens	Human	PF00001	6.3	IC50	ChEMBL;BindingDB
P21917	DRD4	Homo sapiens	Human	PF00001	6.3	IC50	ChEMBL;BindingDB
P28223	HTR2A	Homo sapiens	Human	PF00001	6.2	IC50	ChEMBL;BindingDB
Q01959	SLC6A3	Homo sapiens	Human	PF00209	6.1	IC50	ChEMBL;BindingDB
P08908	HTR1A	Homo sapiens	Human	PF00001	6.0	IC50	ChEMBL;BindingDB
P34969	HTR7	Homo sapiens	Human	PF00001	6.0	IC50	ChEMBL;BindingDB