Molecule Details
InChIKeyFZBAOOQVQXATRL-UHFFFAOYSA-N
Canonical SMILESN#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2cnn3Cc2n[nH]c3ncccc23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL9.23
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12999
Drug NameMK-6186
CAS Number1034474-19-5
Groups investigational
ATC Codes nan
DescriptionMK6186 has been used in trials studying the treatment of HIV-1 Infection.
Cross-references: CHEMBL1939499 ChemSpider: 28424190 PubChem:24988948 PubChem:347829136 ZINC: ZINC000073240561
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9WJQ2 reverse transcriptase Human immunodeficiency virus type 1 Pathogen PF00078 9.2 Ki BindingDB
Q72547 pol Human immunodeficiency virus type 1 Pathogen PF00075 PF00078 PF06815 PF06817 9.2 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P03366 gag-pol Gag-Pol polyprotein inhibitor targets