Molecule Details
InChIKeyFXQWJULRETZHHW-UHFFFAOYSA-N
Compound Name4-[4-(1,3-Benzoxazol-2-ylamino)phenyl]-2,3-dihydroisoindol-1-one
Canonical SMILESO=C1NCc2c1cccc2-c1ccc(Nc2nc3ccccc3o2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.61
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 7.4 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.8 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.5 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.4 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.3 Ki ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.3 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.2 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL