Molecule Details
InChIKeyFXMWUTGUCAKGQL-UHFFFAOYSA-N
Compound Name2,5-Dimethoxy-4-bromoamphetamine
Canonical SMILESCOc1cc(CC(C)N)c(OC)cc1Br
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.78
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01484
Drug NameBrolamfetamine
CAS Number32156-26-6
Groups experimental illicit
ATC Codes nan
Descriptionnan

Categories: Agents producing tachycardia Agents that produce hypertension Amines Amphetamines Antidepressive Agents Central Nervous System Agents Central Nervous System Depressants Ethylamines Hallucinogens Neurotransmitter Agents Phenethylamines Psychotropic Drugs Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin Agents Serotonin Receptor Agonists Sympathomimetics
Cross-references: BindingDB: 50005257 CHEMBL6607 ChemSpider: 55902 Guide to Pharmacology: 163 IUPHAR: 163 PubChem:62065 PubChem:46507989
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P28335 HTR2C Homo sapiens Human PF00001 8.2 Ki BindingDB
P28223 HTR2A Homo sapiens Human PF00001 8.1 Ki ChEMBL;BindingDB
P41595 HTR2B Homo sapiens Human PF00001 8.0 Ki BindingDB
P07550 ADRB2 Homo sapiens Human PF00001 6.5 Ki BindingDB
P34969 HTR7 Homo sapiens Human PF00001 6.3 Ki BindingDB
P28566 HTR1E Homo sapiens Human PF00001 6.2 Ki BindingDB
P18825 ADRA2C Homo sapiens Human PF00001 6.2 Ki BindingDB
P28221 HTR1D Homo sapiens Human PF00001 6.2 Ki BindingDB
P23786 CPT2 Homo sapiens Human PF00755 6.1 Ki BindingDB
P28222 HTR1B Homo sapiens Human PF00001 6.0 Ki BindingDB
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P08908 HTR1A 5-hydroxytryptamine receptor 1A inhibitor targets
P28221 HTR1D 5-hydroxytryptamine receptor 1D inhibitor targets
P28223 HTR2A 5-hydroxytryptamine receptor 2A inhibitor targets