Molecule Details
InChIKeyFWRFPHJSGLYXTD-UHFFFAOYSA-N
Compound NameTinodasertib
Canonical SMILESN#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)cn23)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.87
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18796
Drug NameTinodasertib
CAS Number1464151-33-4
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 375544 CHEMBL4211649 ChemSpider: 71046871 PDB: X8K
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9BUB5 MKNK1 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
Q9HBH9 MKNK2 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P06730 EIF4E Homo sapiens Human PF01652 6.3 IC50 ChEMBL