Molecule Details
InChIKeyFWIJKWMXNHRSRO-UHFFFAOYSA-N
Compound Name1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
Canonical SMILESCn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Homologous
Avg pChEMBL6.42
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02277
Drug Name1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 14831 ChEBI: 47249 CHEMBL87277 ChemSpider: 394072 PDB: BMU PubChem:446816 PubChem:46504956 ZINC: ZINC000000165878
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
O15264 MAPK13 Homo sapiens Human PF00069 6.5 Kd ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.5 Kd ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 6.5 Kd ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 binder targets