Molecule Details
| InChIKey | FVTCOCMWUORHEE-UHFFFAOYSA-N |
|---|---|
| Compound Name | Indolocarbazole deriv. 12j |
| Canonical SMILES | COc1ccc2c3c4c(c5c(ccc6ccn(C)c65)c3n(CCCN3CCOCC3)c2c1)C(=O)NC4=O |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.65 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11802 | CDK4 | Homo sapiens | Human | PF00069 | 7.4 | IC50 | ChEMBL;BindingDB |
| P24385 | CCND1 | Homo sapiens | Human | PF02984 PF00134 | 7.4 | IC50 | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 6.2 | pIC50 | TTD_MultiTarget |
| O96020 | CCNE2 | Homo sapiens | Human | PF02984 PF00134 | 6.1 | IC50 | ChEMBL |
| P24864 | CCNE1 | Homo sapiens | Human | PF02984 PF00134 | 6.1 | IC50 | ChEMBL |