N-[4-[[4-[1-(2-cyanoethyl)pyrazol-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]phenyl]-N'-hydroxyoctanediamide

InChIKey	`FVNKMSONBLQBNG-UHFFFAOYSA-N`
Compound Name	N-[4-[[4-[1-(2-cyanoethyl)pyrazol-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]phenyl]-N'-hydroxyoctanediamide
Canonical SMILES	`N#CCCn1cc(-c2nc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc3[nH]ccc23)cn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.94
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	10.4	IC50	ChEMBL;BindingDB
Q9UBN7	HDAC6	Homo sapiens	Human	PF00850 PF02148	9.1	IC50	ChEMBL;BindingDB
Q13547	HDAC1	Homo sapiens	Human	PF00850	7.3	IC50	ChEMBL;BindingDB