2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-amino)-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-propylidene}-piperidin-1-yl ester

InChIKey	`FUYGKZYSHSZHFI-UHFFFAOYSA-N`
Compound Name	2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-amino)-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-propylidene}-piperidin-1-yl ester
Canonical SMILES	`Cc1cc(COc2ccc(S(=O)(=O)CC(C=C3CCN(OC(=O)C(C)(C)C)CC3)N(O)C=O)cc2)c2ccccc2n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	7.39
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P78536	ADAM17	Homo sapiens	Human	PF16698 PF00200 PF13574	8.5	IC50	ChEMBL
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	6.3	IC50	ChEMBL
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	Clinical	TTD_MultiTarget	TTD_MultiTarget
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	Clinical	TTD_MultiTarget	TTD_MultiTarget