6-(3-amino-1H-indazol-6-yl)-4-N-methylpyrimidine-2,4-diamine

InChIKey	`FUWKNYZEQAGYBA-UHFFFAOYSA-N`
Compound Name	6-(3-amino-1H-indazol-6-yl)-4-N-methylpyrimidine-2,4-diamine
Canonical SMILES	`CNc1cc(-c2ccc3c(N)n[nH]c3c2)nc(N)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.63
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O15530	PDPK1	Homo sapiens	Human	PF14593 PF00069	7.1	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.4	pIC50	TTD_MultiTarget
P36897	TGFBR1	Homo sapiens	Human	PF01064 PF00069 PF08515	6.4	IC50	ChEMBL;BindingDB