Molecule Details
| InChIKey | FUSZCAJFRIHBLV-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[5-(4-pyridin-3-ylthiophen-2-yl)-3-pyridinyl]cyclopropanecarboxamide |
| Canonical SMILES | O=C(Nc1cncc(-c2cc(-c3cccnc3)cs2)c1)C1CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.19 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 7.9 | IC50 | ChEMBL;BindingDB |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 7.1 | IC50 | ChEMBL;BindingDB |
| Q8TF76 | HASPIN | Homo sapiens | Human | PF12330 | 7.1 | IC50 | ChEMBL;BindingDB |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 6.6 | IC50 | ChEMBL;BindingDB |