Molecule Details
InChIKeyFURUXTVZLHCCNA-AWEZNQCLSA-N
Compound NameLiquiritigenin
Canonical SMILESO=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.47
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB03601
Drug Name5-deoxyflavanone
CAS Number578-86-9
Groups experimental
ATC Codes nan
Description5-deoxyflavanone is a solid. This compound belongs to the flavanones. These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3.

Cross-references: BindingDB: 50241408 ChEBI: 28777 CHEMBL252642 ChemSpider: 102790 C09762 PDB: DFV PubChem:114829 PubChem:46505285 ZINC: ZINC000000985403
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P04350 TUBB4A Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
P07437 TUBB Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
P0DPH7 TUBA3C Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
P11511 CYP19A1 Homo sapiens Human PF00067 6.5 IC50 ChEMBL;BindingDB
P68363 TUBA1B Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
P68366 TUBA4A Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
P68371 TUBB4B Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q13509 TUBB3 Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q13885 TUBB2A Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q3ZCM7 TUBB8 Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q6PEY2 TUBA3E Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q71U36 TUBA1A Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q9BQE3 TUBA1C Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q9BUF5 TUBB6 Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q9BVA1 TUBB2B Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
Q9H4B7 TUBB1 Homo sapiens Human PF00091 PF03953 6.5 IC50 ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P11511 CYP19A1 Aromatase inhibitor targets
P47989 XDH Xanthine dehydrogenase/oxidase inhibitor targets