Molecule Details
InChIKeyFSWFKKQQSQHIRZ-UHFFFAOYSA-N
Compound Name5-chloro-7-methylsulfanyl-3,4-dihydro-2H-benzo[b][1,7]naphthyridin-1-one
Canonical SMILESCSc1ccc2nc3c(c(Cl)c2c1)CCNC3=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL6.41
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P11309 PIM1 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.4 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9NR20 DYRK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL