Molecule Details
InChIKeyFSBMCTDYWXIBLM-UHFFFAOYSA-N
Compound NameSEL120-34A free base
Canonical SMILESCc1c(Br)c(Br)c2c3c1nc(N1CCNCC1)n3CCC2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)22
Pfam Stratification Cross-Family
Avg pChEMBL7.59
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18107
Drug NameSEL120-34A free base
CAS Number1609522-33-9
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 50459995 CHEMBL4225966 ChemSpider: 67886362
Target Activities (22)
Target Gene Organism Category Pfam pChEMBL Type Source
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 9.0 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 8.8 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 8.8 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.6 IC50 ChEMBL
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 8.3 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
P24863 CCNC Homo sapiens Human PF16899 PF00134 8.0 IC50 ChEMBL;BindingDB
Q9BWU1 CDK19 Homo sapiens Human PF00069 8.0 IC50 ChEMBL;BindingDB
P49336 CDK8 Homo sapiens Human PF00069 7.8 IC50 ChEMBL;BindingDB
P49760 CLK2 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
Q8TF76 HASPIN Homo sapiens Human PF12330 7.3 IC50 ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 7.3 IC50 ChEMBL
P51948 MNAT1 Homo sapiens Human PF25811 PF06391 PF17121 7.3 IC50 ChEMBL
P05177 CYP1A2 Homo sapiens Human PF00067 7.1 IC50 ChEMBL
Q9H422 HIPK3 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P19784 CSNK2A2 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 6.2 IC50 ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.1 IC50 ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P49336 CDK8 Cyclin-dependent kinase 8 inhibitor targets
Q9BWU1 CDK19 Cyclin-dependent kinase 19 inhibitor targets